Drug interactions
Brompheniramine + Loxapine inhaled
Severity: Moderate
Brompheniramine and Loxapine inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled loxapine is an antipsychotic that causes sedation and has anticholinergic activity, and brompheniramine adds further sedative and antimuscarinic effects. The combination may increase drowsiness and anticholinergic effects.
What this interaction means in plain words
Brompheniramine and Loxapine inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression and additive anticholinergic effects.
What to do
Monitor sedation level after loxapine administration. Avoid driving and consider a non-sedating antihistamine.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Loxapine inhaled?
MediHelp rates the interaction as moderate. Brompheniramine and Loxapine inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Inhaled loxapine is an antipsychotic that causes sedation and has anticholinergic activity, and brompheniramine adds further sedative and antimuscarinic effects. The combination may increase drowsiness and anticholinergic effects.
How serious is the interaction between Brompheniramine and Loxapine inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation level after loxapine administration. Avoid driving and consider a non-sedating antihistamine.
What other medicines interact with Brompheniramine?
MediHelp also lists interactions of Brompheniramine with, for example, Alfentanil, Belladonna and opium, Benzhydrocodone / acetaminophen. The full list is on the Brompheniramine page.
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