Drug interactions
Brompheniramine + Marijuana
Severity: Moderate
Brompheniramine and Marijuana: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cannabis causes sedation, dizziness and impaired psychomotor performance, which brompheniramine may worsen. The combination can also add to tachycardia and anticholinergic effects such as dry mouth.
What this interaction means in plain words
Brompheniramine and Marijuana can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depressant effects; cannabinoids also have additive effects with anticholinergic drugs on heart rate and mucosal dryness.
What to do
Advise the patient to avoid driving and hazardous tasks. Consider a non-sedating antihistamine if cannabis use continues.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Marijuana?
MediHelp rates the interaction as moderate. Brompheniramine and Marijuana can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cannabis causes sedation, dizziness and impaired psychomotor performance, which brompheniramine may worsen. The combination can also add to tachycardia and anticholinergic effects such as dry mouth.
How serious is the interaction between Brompheniramine and Marijuana?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise the patient to avoid driving and hazardous tasks. Consider a non-sedating antihistamine if cannabis use continues.
What other medicines interact with Brompheniramine?
MediHelp also lists interactions of Brompheniramine with, for example, Alfentanil, Belladonna and opium, Benzhydrocodone / acetaminophen. The full list is on the Brompheniramine page.
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