Drug interactions
Brompheniramine + Meprobamate
Severity: Moderate
Brompheniramine and Meprobamate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Meprobamate is a sedative anxiolytic and brompheniramine is a sedating antihistamine. Together they can cause excessive drowsiness, confusion and impaired coordination.
What this interaction means in plain words
Brompheniramine and Meprobamate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive central nervous system depression.
What to do
Avoid alcohol and driving, and reduce the meprobamate dose if oversedation occurs. Use a non-sedating antihistamine if possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Meprobamate?
MediHelp rates the interaction as moderate. Brompheniramine and Meprobamate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Meprobamate is a sedative anxiolytic and brompheniramine is a sedating antihistamine. Together they can cause excessive drowsiness, confusion and impaired coordination.
How serious is the interaction between Brompheniramine and Meprobamate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid alcohol and driving, and reduce the meprobamate dose if oversedation occurs. Use a non-sedating antihistamine if possible.
What other medicines interact with Brompheniramine?
MediHelp also lists interactions of Brompheniramine with, for example, Alfentanil, Belladonna and opium, Benzhydrocodone / acetaminophen. The full list is on the Brompheniramine page.
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