Drug interactions
Brompheniramine + Triprolidine
Severity: Moderate
Brompheniramine and Triprolidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are first-generation antihistamines, so combining them increases drowsiness and anticholinergic effects with no added benefit.
What this interaction means in plain words
Brompheniramine and Triprolidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brompheniramine belongs to Respiratory; Triprolidine belongs to Respiratory.
Why it happens
Additive H1 antagonism, anticholinergic and CNS depressant effects.
What to do
Avoid duplicate antihistamine therapy; use only one agent. Warn about sedation and driving.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Triprolidine
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Triprolidine?
MediHelp rates the interaction as moderate. Brompheniramine and Triprolidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are first-generation antihistamines, so combining them increases drowsiness and anticholinergic effects with no added benefit.
How serious is the interaction between Brompheniramine and Triprolidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid duplicate antihistamine therapy; use only one agent. Warn about sedation and driving.
What other medicines interact with Triprolidine?
MediHelp also lists interactions of Triprolidine with, for example, Belladonna and opium, Benzhydrocodone / acetaminophen, Brexanolone. The full list is on the Triprolidine page.
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