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Drug interactions

Budesonide + Candesartan-hydrochlorothiazide

Severity: Minor

Budesonide and Candesartan-hydrochlorothiazide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Systemic corticosteroids and thiazides both promote potassium loss, and budesonide can contribute when systemic exposure is meaningful, such as with oral or high-dose use. Hypokalemia may result.

What this interaction means in plain words

Budesonide and Candesartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Budesonide belongs to Respiratory; Candesartan-hydrochlorothiazide belongs to Cardiovascular.

Evidence level: Low

Why it happens

Additive kaliuresis from thiazide action and corticosteroid mineralocorticoid effect.

What to do

Monitor serum potassium when budesonide is given systemically or long term. Replace potassium if low.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Budesonide with Candesartan-hydrochlorothiazide?

MediHelp rates the interaction as minor. Budesonide and Candesartan-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroids and thiazides both promote potassium loss, and budesonide can contribute when systemic exposure is meaningful, such as with oral or high-dose use. Hypokalemia may result.

How serious is the interaction between Budesonide and Candesartan-hydrochlorothiazide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium when budesonide is given systemically or long term. Replace potassium if low.

What other medicines interact with Candesartan-hydrochlorothiazide?

MediHelp also lists interactions of Candesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Candesartan-hydrochlorothiazide page.

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