Drug interactions
Budesonide + Celecoxib
Severity: Minor
Budesonide and Celecoxib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids combined with NSAIDs increase the risk of gastrointestinal ulceration and bleeding. With locally acting or inhaled budesonide the added risk is smaller than with systemic steroids, but it is not zero.
What this interaction means in plain words
Budesonide and Celecoxib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Celecoxib belongs to Musculoskeletal.
Why it happens
Additive gastric mucosal injury and impaired healing from corticosteroid and NSAID effects.
What to do
Use the lowest effective doses and consider gastroprotection in patients with GI risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Budesonide with Celecoxib?
MediHelp rates the interaction as minor. Budesonide and Celecoxib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids combined with NSAIDs increase the risk of gastrointestinal ulceration and bleeding. With locally acting or inhaled budesonide the added risk is smaller than with systemic steroids, but it is not zero.
How serious is the interaction between Budesonide and Celecoxib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and consider gastroprotection in patients with GI risk factors.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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