Drug interactions
Budesonide + Cholestyramine
Severity: Moderate
Budesonide and Cholestyramine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cholestyramine binds drugs in the gut and may reduce absorption of oral budesonide, lowering its local and systemic effect. This could compromise disease control.
What this interaction means in plain words
Budesonide and Cholestyramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide belongs to Respiratory; Cholestyramine belongs to Cardiovascular.
Why it happens
Bile acid sequestrant binds budesonide in the gastrointestinal lumen, reducing absorption.
What to do
Separate administration, giving budesonide at least 1 hour before or 4 to 6 hours after cholestyramine, and monitor response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide
Other interactions of Cholestyramine
Frequently asked questions
Can I take Budesonide with Cholestyramine?
MediHelp rates the interaction as moderate. Budesonide and Cholestyramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cholestyramine binds drugs in the gut and may reduce absorption of oral budesonide, lowering its local and systemic effect. This could compromise disease control.
How serious is the interaction between Budesonide and Cholestyramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration, giving budesonide at least 1 hour before or 4 to 6 hours after cholestyramine, and monitor response.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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