Drug interactions
Budesonide + Cimetidine
Severity: Minor
Budesonide and Cimetidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cimetidine is a weak CYP3A4 inhibitor and may modestly raise budesonide levels. The increase is small and rarely clinically important.
What this interaction means in plain words
Budesonide and Cimetidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Cimetidine belongs to Gastrointestinal Tract.
Why it happens
Weak inhibition of CYP3A4-mediated budesonide metabolism.
What to do
No dose adjustment is usually needed. Watch for signs of corticosteroid excess with prolonged oral use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Cimetidine
- Cimetidine + Dofetilide Contraindicated
- Cimetidine + Fezolinetant Contraindicated
- Alfentanil + Cimetidine Major
- Atazanavir + Cimetidine Major
- Carmustine + Cimetidine Major
- Cimetidine + Citalopram Major
Frequently asked questions
Can I take Budesonide with Cimetidine?
MediHelp rates the interaction as minor. Budesonide and Cimetidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cimetidine is a weak CYP3A4 inhibitor and may modestly raise budesonide levels. The increase is small and rarely clinically important.
How serious is the interaction between Budesonide and Cimetidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed. Watch for signs of corticosteroid excess with prolonged oral use.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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