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Drug interactions

Budesonide + Dapagliflozin-metformin

Severity: Minor

Budesonide and Dapagliflozin-metformin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Systemic exposure to budesonide, especially with oral or high-dose use, can raise blood glucose and weaken diabetes control. Inhaled or locally acting formulations have much smaller effects.

What this interaction means in plain words

Budesonide and Dapagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Budesonide belongs to Respiratory; Dapagliflozin-metformin belongs to Endocrine.

Evidence level: Moderate

Why it happens

Pharmacodynamic antagonism through glucocorticoid-induced insulin resistance and increased hepatic glucose output.

What to do

Monitor blood glucose when budesonide is started at systemic or high doses and adjust antidiabetic therapy if needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Budesonide with Dapagliflozin-metformin?

MediHelp rates the interaction as minor. Budesonide and Dapagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic exposure to budesonide, especially with oral or high-dose use, can raise blood glucose and weaken diabetes control. Inhaled or locally acting formulations have much smaller effects.

How serious is the interaction between Budesonide and Dapagliflozin-metformin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when budesonide is started at systemic or high doses and adjust antidiabetic therapy if needed.

What other medicines interact with Dapagliflozin-metformin?

MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.

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