Drug reference
dapagliflozin-metformin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (Glycosurics)
Mechanism of action
Dapagliflozin: Selective sodium-glucose transporter-2 (SGLT2) inhibitor; SGLT2 is expressed in the proximal renal tubules and is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Metformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose.
Common side effects
- Nasopharyngitis
- Headache
- Female genital mycotic infections
- Urinary tract infection
- Diarrhea
Related conditions
Frequently asked questions
What drug class is dapagliflozin-metformin?
dapagliflozin-metformin belongs to: Endocrine.
How does dapagliflozin-metformin work?
Dapagliflozin: Selective sodium-glucose transporter-2 (SGLT2) inhibitor; SGLT2 is expressed in the proximal renal tubules and is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Metformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose.
What are the common side effects of dapagliflozin-metformin?
Nasopharyngitis, Headache, Female genital mycotic infections, Urinary tract infection, Diarrhea
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