Drug interactions
Budesonide + Dexlansoprazole
Severity: Minor
Budesonide and Dexlansoprazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Acid suppression raises gastric pH and may cause premature release from pH-dependent oral budesonide formulations. Clinical consequences are uncertain and often small, and the combination is common in practice.
What this interaction means in plain words
Budesonide and Dexlansoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Dexlansoprazole belongs to Gastrointestinal Tract.
Why it happens
Increased gastric pH may alter dissolution of pH-dependent budesonide coatings.
What to do
No routine change is needed; monitor therapeutic response in patients on oral budesonide for inflammatory bowel disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Dexlansoprazole
- Dexlansoprazole + Mavacamten Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Dexlansoprazole Major
- Atazanavir + Dexlansoprazole Major
- Dacomitinib + Dexlansoprazole Major
- Dasatinib + Dexlansoprazole Major
Frequently asked questions
Can I take Budesonide with Dexlansoprazole?
MediHelp rates the interaction as minor. Budesonide and Dexlansoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Acid suppression raises gastric pH and may cause premature release from pH-dependent oral budesonide formulations. Clinical consequences are uncertain and often small, and the combination is common in practice.
How serious is the interaction between Budesonide and Dexlansoprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor therapeutic response in patients on oral budesonide for inflammatory bowel disease.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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