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Drug interactions

Budesonide + Famotidine

Severity: Minor

Budesonide and Famotidine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Famotidine raises gastric pH and may cause early dissolution of pH-dependent oral budesonide formulations. The clinical effect is probably small.

What this interaction means in plain words

Budesonide and Famotidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Budesonide belongs to Respiratory; Famotidine belongs to Gastrointestinal Tract.

Evidence level: Low

Why it happens

Increased gastric pH may alter dissolution of pH-dependent budesonide coatings.

What to do

Monitor response to oral budesonide; consider dosing the H2 blocker at a different time of day.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Budesonide with Famotidine?

MediHelp rates the interaction as minor. Budesonide and Famotidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Famotidine raises gastric pH and may cause early dissolution of pH-dependent oral budesonide formulations. The clinical effect is probably small.

How serious is the interaction between Budesonide and Famotidine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor response to oral budesonide; consider dosing the H2 blocker at a different time of day.

What other medicines interact with Budesonide?

MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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