Drug interactions
Budesonide + Fosinopril-hydrochlorothiazide
Severity: Minor
Budesonide and Fosinopril-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemically absorbed corticosteroids and thiazides both promote potassium loss, so hypokalemia may be additive. Risk is greater with oral or high-dose budesonide and lower with inhaled or topical forms.
What this interaction means in plain words
Budesonide and Fosinopril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Fosinopril-hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Additive renal potassium wasting from thiazide diuresis and corticosteroid mineralocorticoid activity.
What to do
Monitor serum potassium when systemic budesonide is used with the thiazide, and supplement or adjust therapy if low.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fosinopril-hydrochlorothiazide
- Aliskiren + Fosinopril-hydrochlorothiazide Contraindicated
- Dofetilide + Fosinopril-hydrochlorothiazide Contraindicated
- Fosinopril-hydrochlorothiazide + Protein a column Contraindicated
- Fosinopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aldesleukin + Fosinopril-hydrochlorothiazide Major
- Amifostine + Fosinopril-hydrochlorothiazide Major
Other interactions of Budesonide
Frequently asked questions
Can I take Budesonide with Fosinopril-hydrochlorothiazide?
MediHelp rates the interaction as minor. Budesonide and Fosinopril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemically absorbed corticosteroids and thiazides both promote potassium loss, so hypokalemia may be additive. Risk is greater with oral or high-dose budesonide and lower with inhaled or topical forms.
How serious is the interaction between Budesonide and Fosinopril-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium when systemic budesonide is used with the thiazide, and supplement or adjust therapy if low.
What other medicines interact with Fosinopril-hydrochlorothiazide?
MediHelp also lists interactions of Fosinopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Fosinopril-hydrochlorothiazide page.
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