Drug interactions
Budesonide + Mesterolone
Severity: Minor
Budesonide and Mesterolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgens such as mesterolone can promote sodium and fluid retention, and corticosteroids do the same. Used together, they may add to each other's effect and increase the risk of edema, particularly in patients with heart, kidney or liver disease. With inhaled or locally acting budesonide the effect is small.
What this interaction means in plain words
Budesonide and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Mesterolone belongs to Endocrine.
Why it happens
Additive sodium and water retention through androgenic and mineralocorticoid-type effects.
What to do
Monitor body weight and look for peripheral edema, especially in patients with heart failure, renal impairment or hypertension. Reduce the dose or review therapy if fluid retention develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Mesterolone
Frequently asked questions
Can I take Budesonide with Mesterolone?
MediHelp rates the interaction as minor. Budesonide and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgens such as mesterolone can promote sodium and fluid retention, and corticosteroids do the same. Used together, they may add to each other's effect and increase the risk of edema, particularly in patients with heart, kidney or liver disease. With inhaled or locally acting budesonide the effect is small.
How serious is the interaction between Budesonide and Mesterolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor body weight and look for peripheral edema, especially in patients with heart failure, renal impairment or hypertension. Reduce the dose or review therapy if fluid retention develops.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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