Drug interactions
Budesonide + Nicardipine
Severity: Minor
Budesonide and Nicardipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nicardipine can inhibit CYP3A4 and P-glycoprotein and could modestly raise budesonide exposure. Any effect is likely small, and budesonide does not meaningfully alter nicardipine levels.
What this interaction means in plain words
Budesonide and Nicardipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Nicardipine belongs to Cardiovascular.
Why it happens
Weak inhibition of CYP3A4 and P-glycoprotein by nicardipine may reduce budesonide clearance.
What to do
No routine adjustment is needed; watch for signs of corticosteroid excess with long-term or high-dose oral budesonide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Nicardipine
Frequently asked questions
Can I take Budesonide with Nicardipine?
MediHelp rates the interaction as minor. Budesonide and Nicardipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nicardipine can inhibit CYP3A4 and P-glycoprotein and could modestly raise budesonide exposure. Any effect is likely small, and budesonide does not meaningfully alter nicardipine levels.
How serious is the interaction between Budesonide and Nicardipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; watch for signs of corticosteroid excess with long-term or high-dose oral budesonide.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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