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Drug interactions

Budesonide + Sarecycline

Severity: Minor

Budesonide and Sarecycline: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Sarecycline weakly inhibits P-glycoprotein in vitro, which could slightly raise budesonide absorption. Clinical relevance is probably low.

What this interaction means in plain words

Budesonide and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Budesonide belongs to Respiratory; Sarecycline belongs to Anti Bacterial.

Evidence level: Low

Why it happens

Possible inhibition of P-glycoprotein efflux by sarecycline increasing budesonide exposure.

What to do

No routine action is needed; be alert for corticosteroid adverse effects with prolonged or high-dose budesonide use.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Budesonide with Sarecycline?

MediHelp rates the interaction as minor. Budesonide and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sarecycline weakly inhibits P-glycoprotein in vitro, which could slightly raise budesonide absorption. Clinical relevance is probably low.

How serious is the interaction between Budesonide and Sarecycline?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; be alert for corticosteroid adverse effects with prolonged or high-dose budesonide use.

What other medicines interact with Budesonide?

MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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