Drug interactions
Budesonide + Verapamil
Severity: Minor
Budesonide and Verapamil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Verapamil inhibits CYP3A4 and P-glycoprotein, which may modestly raise systemic budesonide exposure. This could increase corticosteroid effects, particularly with oral budesonide or long-term use.
What this interaction means in plain words
Budesonide and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Budesonide belongs to Respiratory; Verapamil belongs to Cardiovascular.
Why it happens
Inhibition of CYP3A4 metabolism and P-glycoprotein efflux of budesonide by verapamil.
What to do
No routine change is needed; watch for signs of corticosteroid excess during prolonged oral budesonide therapy and reduce the dose if they occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Other interactions of Verapamil
- Dofetilide + Verapamil Contraindicated
- Flibanserin + Verapamil Contraindicated
- Lomitapide + Verapamil Contraindicated
- Lonafarnib + Verapamil Contraindicated
- Pimozide + Verapamil Contraindicated
- Acebutolol + Verapamil Major
Frequently asked questions
Can I take Budesonide with Verapamil?
MediHelp rates the interaction as minor. Budesonide and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Verapamil inhibits CYP3A4 and P-glycoprotein, which may modestly raise systemic budesonide exposure. This could increase corticosteroid effects, particularly with oral budesonide or long-term use.
How serious is the interaction between Budesonide and Verapamil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; watch for signs of corticosteroid excess during prolonged oral budesonide therapy and reduce the dose if they occur.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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