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Drug interactions

Budesonide-formoterol + Celiprolol

Severity: Moderate

Budesonide-formoterol and Celiprolol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Celiprolol is a beta-blocker with beta-1 selectivity and partial beta-2 agonist activity, and it may blunt the bronchodilator effect of formoterol. The risk of bronchospasm is smaller than with nonselective agents but is still relevant in asthma or COPD.

What this interaction means in plain words

Budesonide-formoterol and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Pharmacodynamic antagonism at beta-adrenergic receptors.

What to do

Monitor respiratory symptoms and peak flow, and use the lowest effective celiprolol dose. Consider a non-beta-blocker alternative in patients with reactive airway disease.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Budesonide-formoterol with Celiprolol?

MediHelp rates the interaction as moderate. Budesonide-formoterol and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celiprolol is a beta-blocker with beta-1 selectivity and partial beta-2 agonist activity, and it may blunt the bronchodilator effect of formoterol. The risk of bronchospasm is smaller than with nonselective agents but is still relevant in asthma or COPD.

How serious is the interaction between Budesonide-formoterol and Celiprolol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory symptoms and peak flow, and use the lowest effective celiprolol dose. Consider a non-beta-blocker alternative in patients with reactive airway disease.

What other medicines interact with Budesonide-formoterol?

MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.

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