Drug interactions
Amisulpride + Budesonide-formoterol
Severity: Major
Amisulpride and Budesonide-formoterol: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amisulpride causes dose-related QT prolongation, and formoterol can add tachycardia, hypokalemia and QT effects. Together they raise the risk of torsades de pointes in susceptible patients.
What this interaction means in plain words
Amisulpride and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Budesonide-formoterol belongs to Respiratory.
Why it happens
Additive effects on cardiac repolarization, with beta-agonist-induced hypokalemia.
What to do
Obtain a baseline ECG and monitor it during co-therapy, and correct potassium and magnesium. Consider an alternative if other QT risk factors are present.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Budesonide-formoterol
Other interactions of Amisulpride
- Amiodarone + Amisulpride Contraindicated
- Amisulpride + Arsenic trioxide Contraindicated
- Amisulpride + Disopyramide Contraindicated
- Amisulpride + Dofetilide Contraindicated
- Amisulpride + Droperidol Contraindicated
- Amisulpride + Ibutilide Contraindicated
Frequently asked questions
Can I take Amisulpride with Budesonide-formoterol?
MediHelp rates the interaction as major. Amisulpride and Budesonide-formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amisulpride causes dose-related QT prolongation, and formoterol can add tachycardia, hypokalemia and QT effects. Together they raise the risk of torsades de pointes in susceptible patients.
How serious is the interaction between Amisulpride and Budesonide-formoterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor it during co-therapy, and correct potassium and magnesium. Consider an alternative if other QT risk factors are present.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amitriptyline. The full list is on the Budesonide-formoterol page.
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