Drug interactions
Budesonide-formoterol + Cyclopenthiazide
Severity: Moderate
Budesonide-formoterol and Cyclopenthiazide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclopenthiazide causes renal potassium loss and formoterol shifts potassium into cells, so combined hypokalemia may be more pronounced. This raises arrhythmia risk in susceptible patients.
What this interaction means in plain words
Budesonide-formoterol and Cyclopenthiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from thiazide renal potassium wasting and beta-2 mediated cellular uptake.
What to do
Monitor serum potassium regularly, especially with higher formoterol doses. Replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Budesonide-formoterol and Cyclopenthiazide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Budesonide-formoterol
Frequently asked questions
Can I take Budesonide-formoterol with Cyclopenthiazide?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Cyclopenthiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclopenthiazide causes renal potassium loss and formoterol shifts potassium into cells, so combined hypokalemia may be more pronounced. This raises arrhythmia risk in susceptible patients.
How serious is the interaction between Budesonide-formoterol and Cyclopenthiazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium regularly, especially with higher formoterol doses. Replace potassium as needed.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
