Drug interactions
Budesonide-formoterol + Droperidol
Severity: Major
Budesonide-formoterol and Droperidol: major interaction.
Last updated Sources: Base de donnees publique des medicaments (France)
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Droperidol carries a labeled warning for QT prolongation and torsades de pointes, and formoterol may add to this and lower potassium. The combination raises the risk of serious arrhythmias.
What this interaction means in plain words
Budesonide-formoterol and Droperidol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Additive QT prolongation with beta-2 agonist-associated hypokalemia.
What to do
Avoid if possible; if droperidol is needed, obtain an ECG, correct electrolytes and monitor the rhythm. Use a non-QT-prolonging antiemetic as an alternative.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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References
Other interactions of Budesonide-formoterol
Frequently asked questions
Can I take Budesonide-formoterol with Droperidol?
MediHelp rates the interaction as major. Budesonide-formoterol and Droperidol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Droperidol carries a labeled warning for QT prolongation and torsades de pointes, and formoterol may add to this and lower potassium. The combination raises the risk of serious arrhythmias.
How serious is the interaction between Budesonide-formoterol and Droperidol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; if droperidol is needed, obtain an ECG, correct electrolytes and monitor the rhythm. Use a non-QT-prolonging antiemetic as an alternative.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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