Drug interactions
Budesonide-formoterol + Epinephrine racemic
Severity: Moderate
Budesonide-formoterol and Epinephrine racemic: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Racemic epinephrine is a sympathomimetic that adds to the cardiac stimulation, tachycardia and hypokalemia caused by formoterol. Together they may raise arrhythmia risk.
What this interaction means in plain words
Budesonide-formoterol and Epinephrine racemic can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic stimulation of beta receptors with possible QT prolongation and hypokalemia.
What to do
Monitor heart rate, rhythm and potassium, especially in patients with cardiac disease. Avoid repeated epinephrine dosing beyond what is needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Frequently asked questions
Can I take Budesonide-formoterol with Epinephrine racemic?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Epinephrine racemic can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Racemic epinephrine is a sympathomimetic that adds to the cardiac stimulation, tachycardia and hypokalemia caused by formoterol. Together they may raise arrhythmia risk.
How serious is the interaction between Budesonide-formoterol and Epinephrine racemic?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, rhythm and potassium, especially in patients with cardiac disease. Avoid repeated epinephrine dosing beyond what is needed.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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