Drug interactions
Budesonide-formoterol + Indapamide
Severity: Moderate
Budesonide-formoterol and Indapamide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indapamide can cause hypokalemia and has been associated with QT prolongation. Formoterol also lowers potassium and may prolong QTc, so the combination can increase the risk of arrhythmia.
What this interaction means in plain words
Budesonide-formoterol and Indapamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Indapamide belongs to Cardiovascular.
Why it happens
Additive hypokalemia and QT prolongation.
What to do
Monitor serum potassium and magnesium and replace as needed. Obtain an ECG if other QT-prolonging drugs or cardiac disease are present.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Indapamide
Frequently asked questions
Can I take Budesonide-formoterol with Indapamide?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Indapamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indapamide can cause hypokalemia and has been associated with QT prolongation. Formoterol also lowers potassium and may prolong QTc, so the combination can increase the risk of arrhythmia.
How serious is the interaction between Budesonide-formoterol and Indapamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium and replace as needed. Obtain an ECG if other QT-prolonging drugs or cardiac disease are present.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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