Drug interactions
Budesonide-formoterol + Lumefantrine
Severity: Moderate
Budesonide-formoterol and Lumefantrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lumefantrine, given with artemether, can prolong the QT interval and formoterol may add to the effect. The combination increases arrhythmia risk, especially with electrolyte disturbance.
What this interaction means in plain words
Budesonide-formoterol and Lumefantrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QTc prolongation, with beta-agonist induced hypokalemia.
What to do
Check potassium and magnesium and consider ECG in patients with cardiac risk during the antimalarial course. Avoid in congenital long QT.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Frequently asked questions
Can I take Budesonide-formoterol with Lumefantrine?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Lumefantrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lumefantrine, given with artemether, can prolong the QT interval and formoterol may add to the effect. The combination increases arrhythmia risk, especially with electrolyte disturbance.
How serious is the interaction between Budesonide-formoterol and Lumefantrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and consider ECG in patients with cardiac risk during the antimalarial course. Avoid in congenital long QT.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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