Drug interactions
Budesonide-formoterol + Norepinephrine
Severity: Moderate
Budesonide-formoterol and Norepinephrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Norepinephrine is a potent vasopressor and formoterol adds beta-adrenergic stimulation. Together they can increase heart rate, blood pressure and arrhythmia risk, and formoterol may lower serum potassium.
What this interaction means in plain words
Budesonide-formoterol and Norepinephrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic stimulation of cardiac beta receptors, with beta-2 mediated potassium shift.
What to do
Monitor ECG, blood pressure and serum potassium when norepinephrine is infused in a patient on formoterol. Titrate the vasopressor to effect.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Frequently asked questions
Can I take Budesonide-formoterol with Norepinephrine?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Norepinephrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Norepinephrine is a potent vasopressor and formoterol adds beta-adrenergic stimulation. Together they can increase heart rate, blood pressure and arrhythmia risk, and formoterol may lower serum potassium.
How serious is the interaction between Budesonide-formoterol and Norepinephrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, blood pressure and serum potassium when norepinephrine is infused in a patient on formoterol. Titrate the vasopressor to effect.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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