Drug interactions
Budesonide-formoterol + Octreotide
Severity: Moderate
Budesonide-formoterol and Octreotide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Octreotide can cause bradycardia and QT prolongation, and formoterol may add to repolarisation effects and lower potassium. The combined effect is generally modest but may matter in patients with cardiac disease.
What this interaction means in plain words
Budesonide-formoterol and Octreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Budesonide-formoterol belongs to Respiratory; Octreotide belongs to Endocrine.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia.
What to do
Monitor ECG and electrolytes in patients with cardiac disease or other QT risk factors. No routine change is needed otherwise.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Budesonide-formoterol
Other interactions of Octreotide
Frequently asked questions
Can I take Budesonide-formoterol with Octreotide?
MediHelp rates the interaction as moderate. Budesonide-formoterol and Octreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Octreotide can cause bradycardia and QT prolongation, and formoterol may add to repolarisation effects and lower potassium. The combined effect is generally modest but may matter in patients with cardiac disease.
How serious is the interaction between Budesonide-formoterol and Octreotide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes in patients with cardiac disease or other QT risk factors. No routine change is needed otherwise.
What other medicines interact with Budesonide-formoterol?
MediHelp also lists interactions of Budesonide-formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Budesonide-formoterol page.
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