Drug interactions
Buprenorphine subdermal implant + Vardenafil
Severity: Minor
Buprenorphine subdermal implant and Vardenafil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have been associated with QT prolongation, so together they may add to arrhythmia risk. Buprenorphine implant exposure is low and steady, so the effect is likely small.
What this interaction means in plain words
Buprenorphine subdermal implant and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive QT interval prolongation.
What to do
No routine action is needed; consider an ECG in patients with long QT, cardiac disease or other QT-prolonging drugs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Frequently asked questions
Can I take Buprenorphine subdermal implant with Vardenafil?
MediHelp rates the interaction as minor. Buprenorphine subdermal implant and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs have been associated with QT prolongation, so together they may add to arrhythmia risk. Buprenorphine implant exposure is low and steady, so the effect is likely small.
How serious is the interaction between Buprenorphine subdermal implant and Vardenafil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; consider an ECG in patients with long QT, cardiac disease or other QT-prolonging drugs.
What other medicines interact with Vardenafil?
MediHelp also lists interactions of Vardenafil with, for example, Amyl nitrite, Glyceryl trinitrate pr, Isosorbide dinitrate. The full list is on the Vardenafil page.
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