Drug interactions
Butabarbital + Levetiracetam
Severity: Moderate
Butabarbital and Levetiracetam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Butabarbital is a sedative barbiturate, and levetiracetam also causes somnolence and dizziness. Concurrent use may produce excessive sedation and psychomotor impairment.
What this interaction means in plain words
Butabarbital and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression.
What to do
Start with low doses and monitor for sedation and impaired alertness. Avoid alcohol and advise against driving until the response is known.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levetiracetam
Frequently asked questions
Can I take Butabarbital with Levetiracetam?
MediHelp rates the interaction as moderate. Butabarbital and Levetiracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Butabarbital is a sedative barbiturate, and levetiracetam also causes somnolence and dizziness. Concurrent use may produce excessive sedation and psychomotor impairment.
How serious is the interaction between Butabarbital and Levetiracetam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start with low doses and monitor for sedation and impaired alertness. Avoid alcohol and advise against driving until the response is known.
What other medicines interact with Levetiracetam?
MediHelp also lists interactions of Levetiracetam with, for example, Oliceridine, Opium tincture, Sodium oxybate. The full list is on the Levetiracetam page.
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