Drug interactions
Butabarbital + Nadolol
Severity: Minor
Butabarbital and Nadolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Barbiturates induce hepatic enzymes and can lower beta-blocker levels, but nadolol is mainly renally eliminated, so a clinically relevant effect is unlikely.
What this interaction means in plain words
Butabarbital and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Hepatic enzyme induction; nadolol is minimally metabolized so the impact is small.
What to do
No dose adjustment is routinely needed; monitor heart rate and blood pressure if barbiturate therapy is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Butabarbital and Nadolol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Nadolol
Frequently asked questions
Can I take Butabarbital with Nadolol?
MediHelp rates the interaction as minor. Butabarbital and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Barbiturates induce hepatic enzymes and can lower beta-blocker levels, but nadolol is mainly renally eliminated, so a clinically relevant effect is unlikely.
How serious is the interaction between Butabarbital and Nadolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is routinely needed; monitor heart rate and blood pressure if barbiturate therapy is started or stopped.
What other medicines interact with Nadolol?
MediHelp also lists interactions of Nadolol with, for example, Acebutolol, Adrenaline-articaine, Amifostine. The full list is on the Nadolol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
