Drug interactions
Butalbital + Cilostazol
Severity: Minor
Butalbital and Cilostazol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Butalbital is a barbiturate with CYP3A4-inducing potential and may reduce cilostazol exposure. The effect is likely modest with intermittent use, and clinical data are sparse.
What this interaction means in plain words
Butalbital and Cilostazol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible CYP3A4 induction by butalbital increases cilostazol metabolism.
What to do
No routine change is needed; monitor claudication response if butalbital is used frequently.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cilostazol
Frequently asked questions
Can I take Butalbital with Cilostazol?
MediHelp rates the interaction as minor. Butalbital and Cilostazol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Butalbital is a barbiturate with CYP3A4-inducing potential and may reduce cilostazol exposure. The effect is likely modest with intermittent use, and clinical data are sparse.
How serious is the interaction between Butalbital and Cilostazol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor claudication response if butalbital is used frequently.
What other medicines interact with Cilostazol?
MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Anagrelide, Betrixaban. The full list is on the Cilostazol page.
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