Drug interactions
Butalbital + Nadolol
Severity: Minor
Butalbital and Nadolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Butalbital is a barbiturate and enzyme inducer, but nadolol is largely excreted unchanged by the kidneys, so a meaningful decrease in nadolol effect is unlikely.
What this interaction means in plain words
Butalbital and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Hepatic enzyme induction; limited relevance because nadolol is minimally metabolized.
What to do
No routine dose change; monitor blood pressure and heart rate if use is regular or prolonged.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nadolol
Frequently asked questions
Can I take Butalbital with Nadolol?
MediHelp rates the interaction as minor. Butalbital and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Butalbital is a barbiturate and enzyme inducer, but nadolol is largely excreted unchanged by the kidneys, so a meaningful decrease in nadolol effect is unlikely.
How serious is the interaction between Butalbital and Nadolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change; monitor blood pressure and heart rate if use is regular or prolonged.
What other medicines interact with Nadolol?
MediHelp also lists interactions of Nadolol with, for example, Acebutolol, Adrenaline-articaine, Amifostine. The full list is on the Nadolol page.
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