Drug interactions
Butalbital + Nebivolol
Severity: Minor
Butalbital and Nebivolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Butalbital, a barbiturate, can induce hepatic enzymes and may reduce nebivolol exposure, possibly weakening heart rate and blood pressure control. The effect is likely small with intermittent use.
What this interaction means in plain words
Butalbital and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Barbiturate enzyme induction increases hepatic metabolism of nebivolol.
What to do
Monitor blood pressure and heart rate if butalbital is used regularly, and adjust nebivolol dose to response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Butalbital with Nebivolol?
MediHelp rates the interaction as minor. Butalbital and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Butalbital, a barbiturate, can induce hepatic enzymes and may reduce nebivolol exposure, possibly weakening heart rate and blood pressure control. The effect is likely small with intermittent use.
How serious is the interaction between Butalbital and Nebivolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate if butalbital is used regularly, and adjust nebivolol dose to response.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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