Drug interactions
Butorphanol + Levetiracetam
Severity: Minor
Butorphanol and Levetiracetam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levetiracetam commonly causes somnolence, dizziness and fatigue, which may be enhanced by an opioid. The overall risk is modest, but patients may experience more psychomotor impairment.
What this interaction means in plain words
Butorphanol and Levetiracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Butorphanol belongs to Musculoskeletal; Levetiracetam belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects; no pharmacokinetic interaction is established.
What to do
Monitor for increased drowsiness and dizziness, especially when starting or increasing doses. Advise patients to avoid driving until the response is known.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Butorphanol
- Butorphanol + Olanzapine / samidorphan Contraindicated
- Butorphanol + Sodium oxybate Contraindicated
- Alfentanil + Butorphanol Major
- Alprazolam + Butorphanol Major
- Alvimopan + Butorphanol Major
- Amobarbital + Butorphanol Major
Other interactions of Levetiracetam
Frequently asked questions
Can I take Butorphanol with Levetiracetam?
MediHelp rates the interaction as minor. Butorphanol and Levetiracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Levetiracetam commonly causes somnolence, dizziness and fatigue, which may be enhanced by an opioid. The overall risk is modest, but patients may experience more psychomotor impairment.
How serious is the interaction between Butorphanol and Levetiracetam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased drowsiness and dizziness, especially when starting or increasing doses. Advise patients to avoid driving until the response is known.
What other medicines interact with Butorphanol?
MediHelp also lists interactions of Butorphanol with, for example, Olanzapine / samidorphan, Sodium oxybate, Alfentanil. The full list is on the Butorphanol page.
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