Drug interactions
Caffeine + Formoterol
Severity: Minor
Caffeine and Formoterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Caffeine and formoterol are both stimulants of the cardiovascular system, and high caffeine intake may add to tremor, tachycardia and palpitations. Caffeine can also modestly contribute to lower potassium with beta-agonists.
What this interaction means in plain words
Caffeine and Formoterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Caffeine belongs to Miscellaneous; Formoterol belongs to Respiratory.
Why it happens
Additive sympathomimetic and cardiac stimulant effects.
What to do
Advise patients to limit large amounts of caffeine if tremor or palpitations occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Caffeine
- Caffeine + Ephedrine Major
- Caffeine + Fezolinetant Major
- Caffeine + Methylenedioxymethamphetamine Major
- Caffeine + Selegiline transdermal Major
- Adenosine + Caffeine Moderate
- Benzphetamine + Caffeine Moderate
Frequently asked questions
Can I take Caffeine with Formoterol?
MediHelp rates the interaction as minor. Caffeine and Formoterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Caffeine and formoterol are both stimulants of the cardiovascular system, and high caffeine intake may add to tremor, tachycardia and palpitations. Caffeine can also modestly contribute to lower potassium with beta-agonists.
How serious is the interaction between Caffeine and Formoterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to limit large amounts of caffeine if tremor or palpitations occur.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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