Drug interactions
Calcium + Cortisone
Severity: Minor
Calcium and Cortisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids lower intestinal calcium absorption and increase urinary calcium loss. With long-term use this contributes to bone loss, and calcium intake may be less effective.
What this interaction means in plain words
Calcium and Cortisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucocorticoids reduce intestinal calcium absorption and increase renal calcium excretion.
What to do
Ensure adequate calcium and vitamin D intake during prolonged corticosteroid therapy and assess bone health as indicated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Frequently asked questions
Can I take Calcium with Cortisone?
MediHelp rates the interaction as minor. Calcium and Cortisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroids lower intestinal calcium absorption and increase urinary calcium loss. With long-term use this contributes to bone loss, and calcium intake may be less effective.
How serious is the interaction between Calcium and Cortisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure adequate calcium and vitamin D intake during prolonged corticosteroid therapy and assess bone health as indicated.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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