Drug interactions
Calcium + Elvitegravir
Severity: Moderate
Calcium and Elvitegravir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium-containing antacids lower elvitegravir plasma concentrations, which may compromise virologic control and promote resistance.
What this interaction means in plain words
Calcium and Elvitegravir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Calcium forms ionic complexes with elvitegravir in the gut, decreasing absorption.
What to do
Separate elvitegravir and calcium antacids by at least 2 hours. Follow labeling for the specific combination product.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Frequently asked questions
Can I take Calcium with Elvitegravir?
MediHelp rates the interaction as moderate. Calcium and Elvitegravir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium-containing antacids lower elvitegravir plasma concentrations, which may compromise virologic control and promote resistance.
How serious is the interaction between Calcium and Elvitegravir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate elvitegravir and calcium antacids by at least 2 hours. Follow labeling for the specific combination product.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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