Drug interactions
Calcium chloride + Prednisone
Severity: Minor
Calcium chloride and Prednisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids reduce intestinal calcium absorption and increase urinary calcium loss. Effects on intravenous calcium are limited, but long-term steroid use affects calcium balance.
What this interaction means in plain words
Calcium chloride and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucocorticoids increase renal calcium excretion and reduce intestinal absorption.
What to do
Monitor serum calcium when treating hypocalcemia in patients on prolonged prednisone and adjust the calcium dose to response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Frequently asked questions
Can I take Calcium chloride with Prednisone?
MediHelp rates the interaction as minor. Calcium chloride and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids reduce intestinal calcium absorption and increase urinary calcium loss. Effects on intravenous calcium are limited, but long-term steroid use affects calcium balance.
How serious is the interaction between Calcium chloride and Prednisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium when treating hypocalcemia in patients on prolonged prednisone and adjust the calcium dose to response.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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