Drug interactions
Canakinumab + Hepatitis A vaccine inactivated
Severity: Minor
Canakinumab and Hepatitis A vaccine inactivated: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Canakinumab blocks IL-1 beta, but inactivated vaccines can generally be given, and responses to inactivated vaccines have been preserved in available data. The interaction is of limited concern.
What this interaction means in plain words
Canakinumab and Hepatitis A vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Canakinumab belongs to Miscellaneous; Hepatitis A vaccine inactivated belongs to Anti Virals.
Why it happens
IL-1 beta blockade has little effect on antibody responses to non-replicating vaccines.
What to do
Give hepatitis A vaccine as scheduled; no special precautions beyond routine follow-up.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hepatitis A vaccine inactivated
- Adalimumab + Hepatitis A vaccine inactivated Moderate
- Alefacept + Hepatitis A vaccine inactivated Moderate
- Anakinra + Hepatitis A vaccine inactivated Moderate
- Anti-thymocyte + Hepatitis A vaccine inactivated Moderate
- Antithymocyte globulin equine + Hepatitis A vaccine inactivated Moderate
- Antithymocyte globulin rabbit + Hepatitis A vaccine inactivated Moderate
Other interactions of Canakinumab
- Adalimumab + Canakinumab Major
- Anakinra + Canakinumab Major
- Baricitinib + Canakinumab Major
- Basiliximab + Canakinumab Major
- Canakinumab + Etanercept Major
- Canakinumab + Golimumab Major
Frequently asked questions
Can I take Canakinumab with Hepatitis A vaccine inactivated?
MediHelp rates the interaction as minor. Canakinumab and Hepatitis A vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Canakinumab blocks IL-1 beta, but inactivated vaccines can generally be given, and responses to inactivated vaccines have been preserved in available data. The interaction is of limited concern.
How serious is the interaction between Canakinumab and Hepatitis A vaccine inactivated?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give hepatitis A vaccine as scheduled; no special precautions beyond routine follow-up.
What other medicines interact with Hepatitis A vaccine inactivated?
MediHelp also lists interactions of Hepatitis A vaccine inactivated with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Hepatitis A vaccine inactivated page.
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