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Drug interactions

Candesartan + Insulin degludec-liraglutide

Severity: Minor

Candesartan and Insulin degludec-liraglutide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Candesartan may slightly improve insulin sensitivity and add to the glucose-lowering effect of insulin and liraglutide. Clinically relevant hypoglycemia is uncommon but possible.

What this interaction means in plain words

Candesartan and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Candesartan belongs to Cardiovascular; Insulin degludec-liraglutide belongs to Endocrine.

Evidence level: Low

Why it happens

Angiotensin II receptor blockade may improve insulin sensitivity, adding to the glucose-lowering action of the antidiabetic drugs.

What to do

Monitor blood glucose when candesartan is started or stopped, and adjust the insulin dose if glucose falls.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Candesartan with Insulin degludec-liraglutide?

MediHelp rates the interaction as minor. Candesartan and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Candesartan may slightly improve insulin sensitivity and add to the glucose-lowering effect of insulin and liraglutide. Clinically relevant hypoglycemia is uncommon but possible.

How serious is the interaction between Candesartan and Insulin degludec-liraglutide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when candesartan is started or stopped, and adjust the insulin dose if glucose falls.

What other medicines interact with Insulin degludec-liraglutide?

MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.

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