Drug interactions
Candesartan + Insulin glargine-lixisenatide
Severity: Minor
Candesartan and Insulin glargine-lixisenatide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may enhance insulin sensitivity and occasionally cause hypoglycemia in patients on insulin. The effect is usually small.
What this interaction means in plain words
Candesartan and Insulin glargine-lixisenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Candesartan belongs to Cardiovascular; Insulin glargine-lixisenatide belongs to Endocrine.
Why it happens
Probable improvement in insulin sensitivity from renin-angiotensin blockade; mechanism not fully established.
What to do
Monitor blood glucose when candesartan is started or the dose changed, and adjust insulin if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin glargine-lixisenatide
- Albiglutide + Insulin glargine-lixisenatide Major
- Chlorpropamide + Insulin glargine-lixisenatide Major
- Dulaglutide + Insulin glargine-lixisenatide Major
- Ethanol + Insulin glargine-lixisenatide Major
- Exenatide injectable + Insulin glargine-lixisenatide Major
- Glimepiride + Insulin glargine-lixisenatide Major
Other interactions of Candesartan
- Aliskiren + Candesartan Contraindicated
- Candesartan + Sparsentan Contraindicated
- Amifostine + Candesartan Major
- Amiloride + Candesartan Major
- Amlodipine-benazepril + Candesartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Candesartan Major
Frequently asked questions
Can I take Candesartan with Insulin glargine-lixisenatide?
MediHelp rates the interaction as minor. Candesartan and Insulin glargine-lixisenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may enhance insulin sensitivity and occasionally cause hypoglycemia in patients on insulin. The effect is usually small.
How serious is the interaction between Candesartan and Insulin glargine-lixisenatide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when candesartan is started or the dose changed, and adjust insulin if hypoglycemia occurs.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
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