Drug interactions
Candesartan-hydrochlorothiazide + Celiprolol
Severity: Minor
Candesartan-hydrochlorothiazide and Celiprolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol adds to the blood pressure lowering effect of candesartan and hydrochlorothiazide, which is often intended. Hydrochlorothiazide can reduce celiprolol absorption and thereby its exposure. Potassium effects are modest.
What this interaction means in plain words
Candesartan-hydrochlorothiazide and Celiprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive effect, together with reduced oral absorption of celiprolol in the presence of hydrochlorothiazide.
What to do
Monitor blood pressure and heart rate when starting or adjusting therapy. Titrate doses to response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Candesartan-hydrochlorothiazide
- Aliskiren + Candesartan-hydrochlorothiazide Contraindicated
- Candesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Candesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Candesartan-hydrochlorothiazide Major
- Amifostine + Candesartan-hydrochlorothiazide Major
- Amiloride + Candesartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Candesartan-hydrochlorothiazide with Celiprolol?
MediHelp rates the interaction as minor. Candesartan-hydrochlorothiazide and Celiprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Celiprolol adds to the blood pressure lowering effect of candesartan and hydrochlorothiazide, which is often intended. Hydrochlorothiazide can reduce celiprolol absorption and thereby its exposure. Potassium effects are modest.
How serious is the interaction between Candesartan-hydrochlorothiazide and Celiprolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting therapy. Titrate doses to response.
What other medicines interact with Candesartan-hydrochlorothiazide?
MediHelp also lists interactions of Candesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Candesartan-hydrochlorothiazide page.
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