Drug interactions
Candesartan-hydrochlorothiazide + Cornsilk
Severity: Minor
Candesartan-hydrochlorothiazide and Cornsilk: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cornsilk is a herbal product with reported mild diuretic activity. It may in theory add to the potassium loss and volume depletion of hydrochlorothiazide. Clinical data are scarce.
What this interaction means in plain words
Candesartan-hydrochlorothiazide and Cornsilk have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive diuretic and kaliuretic effect; the mechanism is not well established.
What to do
Check serum potassium if cornsilk is used regularly. Advise patients to report symptoms of dehydration or weakness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Candesartan-hydrochlorothiazide
- Aliskiren + Candesartan-hydrochlorothiazide Contraindicated
- Candesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Candesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Candesartan-hydrochlorothiazide Major
- Amifostine + Candesartan-hydrochlorothiazide Major
- Amiloride + Candesartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Candesartan-hydrochlorothiazide with Cornsilk?
MediHelp rates the interaction as minor. Candesartan-hydrochlorothiazide and Cornsilk have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cornsilk is a herbal product with reported mild diuretic activity. It may in theory add to the potassium loss and volume depletion of hydrochlorothiazide. Clinical data are scarce.
How serious is the interaction between Candesartan-hydrochlorothiazide and Cornsilk?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium if cornsilk is used regularly. Advise patients to report symptoms of dehydration or weakness.
What other medicines interact with Candesartan-hydrochlorothiazide?
MediHelp also lists interactions of Candesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Candesartan-hydrochlorothiazide page.
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