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Drug interactions

Candesartan-hydrochlorothiazide + Mometasone inhaled

Severity: Minor

Candesartan-hydrochlorothiazide and Mometasone inhaled: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Systemic corticosteroids increase potassium loss and may add to thiazide-induced hypokalemia. With inhaled mometasone systemic exposure is low, so the effect is usually small.

What this interaction means in plain words

Candesartan-hydrochlorothiazide and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Mineralocorticoid activity of corticosteroids increases renal potassium excretion, adding to the thiazide effect.

What to do

No routine action is needed at usual inhaled doses; check potassium if high doses are used or other risk factors for hypokalemia exist.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Candesartan-hydrochlorothiazide with Mometasone inhaled?

MediHelp rates the interaction as minor. Candesartan-hydrochlorothiazide and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroids increase potassium loss and may add to thiazide-induced hypokalemia. With inhaled mometasone systemic exposure is low, so the effect is usually small.

How serious is the interaction between Candesartan-hydrochlorothiazide and Mometasone inhaled?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed at usual inhaled doses; check potassium if high doses are used or other risk factors for hypokalemia exist.

What other medicines interact with Candesartan-hydrochlorothiazide?

MediHelp also lists interactions of Candesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Candesartan-hydrochlorothiazide page.

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