Drug interactions
Candesartan-hydrochlorothiazide + Reishi
Severity: Minor
Candesartan-hydrochlorothiazide and Reishi: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reishi mushroom has been suggested to lower blood pressure, so it could add to the effect of an ARB and thiazide combination. Clinical data are scarce and the effect is probably small.
What this interaction means in plain words
Candesartan-hydrochlorothiazide and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive blood pressure lowering; the mechanism is not well established.
What to do
Monitor blood pressure if the patient starts or stops reishi products, and adjust antihypertensive therapy only if hypotension or loss of control occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Candesartan-hydrochlorothiazide
- Aliskiren + Candesartan-hydrochlorothiazide Contraindicated
- Candesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Candesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Candesartan-hydrochlorothiazide Major
- Amifostine + Candesartan-hydrochlorothiazide Major
- Amiloride + Candesartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Candesartan-hydrochlorothiazide with Reishi?
MediHelp rates the interaction as minor. Candesartan-hydrochlorothiazide and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reishi mushroom has been suggested to lower blood pressure, so it could add to the effect of an ARB and thiazide combination. Clinical data are scarce and the effect is probably small.
How serious is the interaction between Candesartan-hydrochlorothiazide and Reishi?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if the patient starts or stops reishi products, and adjust antihypertensive therapy only if hypotension or loss of control occurs.
What other medicines interact with Candesartan-hydrochlorothiazide?
MediHelp also lists interactions of Candesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Candesartan-hydrochlorothiazide page.
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