Drug interactions
Captopril-hydrochlorothiazide + Cornsilk
Severity: Minor
Captopril-hydrochlorothiazide and Cornsilk: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cornsilk is a herbal product with mild diuretic and potassium-lowering properties reported. With hydrochlorothiazide it could add to potassium and fluid loss, though captopril may partly offset this. The evidence is largely theoretical.
What this interaction means in plain words
Captopril-hydrochlorothiazide and Cornsilk have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive diuretic and kaliuretic effect; the mechanism of the herb is not well established.
What to do
Check serum potassium and blood pressure if cornsilk is used regularly with this product. Advise patients to avoid herbal diuretics unless discussed with their clinician.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Captopril-hydrochlorothiazide with Cornsilk?
MediHelp rates the interaction as minor. Captopril-hydrochlorothiazide and Cornsilk have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cornsilk is a herbal product with mild diuretic and potassium-lowering properties reported. With hydrochlorothiazide it could add to potassium and fluid loss, though captopril may partly offset this. The evidence is largely theoretical.
How serious is the interaction between Captopril-hydrochlorothiazide and Cornsilk?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium and blood pressure if cornsilk is used regularly with this product. Advise patients to avoid herbal diuretics unless discussed with their clinician.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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