Drug interactions
Captopril-hydrochlorothiazide + Fo-ti
Severity: Minor
Captopril-hydrochlorothiazide and Fo-ti: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fo-ti contains anthraquinones with laxative activity, which may cause potassium loss. This could add to the hypokalemia from hydrochlorothiazide, though the evidence is theoretical.
What this interaction means in plain words
Captopril-hydrochlorothiazide and Fo-ti have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive potassium loss via laxative effect; not firmly established.
What to do
Monitor serum potassium if fo-ti is used regularly, and advise against prolonged use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Captopril-hydrochlorothiazide with Fo-ti?
MediHelp rates the interaction as minor. Captopril-hydrochlorothiazide and Fo-ti have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fo-ti contains anthraquinones with laxative activity, which may cause potassium loss. This could add to the hypokalemia from hydrochlorothiazide, though the evidence is theoretical.
How serious is the interaction between Captopril-hydrochlorothiazide and Fo-ti?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if fo-ti is used regularly, and advise against prolonged use.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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