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Drug interactions

Captopril-hydrochlorothiazide + Forskolin

Severity: Minor

Captopril-hydrochlorothiazide and Forskolin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Forskolin raises cyclic AMP and has vasodilating effects that may lower blood pressure. It could add modestly to the effect of the antihypertensive combination, but clinical data are lacking.

What this interaction means in plain words

Captopril-hydrochlorothiazide and Forskolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical additive vasodilation through adenylyl cyclase activation.

What to do

Monitor blood pressure if forskolin supplements are started or stopped.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Captopril-hydrochlorothiazide with Forskolin?

MediHelp rates the interaction as minor. Captopril-hydrochlorothiazide and Forskolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Forskolin raises cyclic AMP and has vasodilating effects that may lower blood pressure. It could add modestly to the effect of the antihypertensive combination, but clinical data are lacking.

How serious is the interaction between Captopril-hydrochlorothiazide and Forskolin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if forskolin supplements are started or stopped.

What other medicines interact with Captopril-hydrochlorothiazide?

MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.

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