Drug interactions
Captopril-hydrochlorothiazide + Iloprost inhaled
Severity: Moderate
Captopril-hydrochlorothiazide and Iloprost inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost is a prostacyclin vasodilator and inhaled use may add to the blood pressure lowering of captopril and hydrochlorothiazide. Systemic absorption is modest, but dizziness or hypotension may occur.
What this interaction means in plain words
Captopril-hydrochlorothiazide and Iloprost inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive vasodilation and blood pressure lowering.
What to do
Monitor blood pressure when iloprost is started, especially in patients on multiple antihypertensives. Lower antihypertensive doses if symptomatic hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Captopril-hydrochlorothiazide with Iloprost inhaled?
MediHelp rates the interaction as moderate. Captopril-hydrochlorothiazide and Iloprost inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloprost is a prostacyclin vasodilator and inhaled use may add to the blood pressure lowering of captopril and hydrochlorothiazide. Systemic absorption is modest, but dizziness or hypotension may occur.
How serious is the interaction between Captopril-hydrochlorothiazide and Iloprost inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when iloprost is started, especially in patients on multiple antihypertensives. Lower antihypertensive doses if symptomatic hypotension develops.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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