Drug interactions
Captopril-hydrochlorothiazide + Juniper
Severity: Minor
Captopril-hydrochlorothiazide and Juniper: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Juniper has diuretic properties and might add to the fluid and electrolyte loss produced by hydrochlorothiazide. Large doses may harm the kidneys, which is relevant with an ACE inhibitor and diuretic.
What this interaction means in plain words
Captopril-hydrochlorothiazide and Juniper have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive diuretic effect; clinical data are limited and the interaction is largely theoretical.
What to do
Advise patients to avoid juniper supplements, or monitor blood pressure, electrolytes and renal function if used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Captopril-hydrochlorothiazide with Juniper?
MediHelp rates the interaction as minor. Captopril-hydrochlorothiazide and Juniper have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Juniper has diuretic properties and might add to the fluid and electrolyte loss produced by hydrochlorothiazide. Large doses may harm the kidneys, which is relevant with an ACE inhibitor and diuretic.
How serious is the interaction between Captopril-hydrochlorothiazide and Juniper?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid juniper supplements, or monitor blood pressure, electrolytes and renal function if used.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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