Drug interactions
Captopril-hydrochlorothiazide + Mometasone inhaled
Severity: Minor
Captopril-hydrochlorothiazide and Mometasone inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids can lower potassium and add to the hypokalemic effect of thiazides. With inhaled mometasone, systemic exposure is low, so the effect is usually small.
What this interaction means in plain words
Captopril-hydrochlorothiazide and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mineralocorticoid activity of corticosteroids adds to thiazide-induced renal potassium loss; minimal at inhaled doses.
What to do
No routine action; check serum potassium if the patient has other risk factors for hypokalemia or uses high doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Captopril-hydrochlorothiazide with Mometasone inhaled?
MediHelp rates the interaction as minor. Captopril-hydrochlorothiazide and Mometasone inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids can lower potassium and add to the hypokalemic effect of thiazides. With inhaled mometasone, systemic exposure is low, so the effect is usually small.
How serious is the interaction between Captopril-hydrochlorothiazide and Mometasone inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; check serum potassium if the patient has other risk factors for hypokalemia or uses high doses.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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